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Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM50445349'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50445349(CHEMBL3104261 | US9676701, 63 Enantiomers of 4R...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50445349(CHEMBL3104261 | US9676701, 63 Enantiomers of 4R...)
Affinity DataKi:  50nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:Briefly, a fixed amount of LSD1 was incubated on ice for 15 minutes, in the absence and/or in the presence of various concentrations of inhibitor (e....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50445349(CHEMBL3104261 | US9676701, 63 Enantiomers of 4R...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant LSD1 using dimethylated H3K4 peptide as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM50445349(CHEMBL3104261 | US9676701, 63 Enantiomers of 4R...)
Affinity DataIC50:  4.05E+4nMAssay Description:Inhibition of human recombinant LSD1 by horseradish peroxidase-coupled fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed