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Found 3 Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 5' and Ligand = 'BDBM175242'
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Confluence Life Sciences

US Patent
LigandPNGBDBM175242(US11844801, Compound (M)-I | US9115089, 49)
Affinity DataIC50:  8.10E+3nMpH: 7.5Assay Description:The ability of compounds to inhibit activated phospho-p38alpha is evaluated using a p38alpha /MK2 and a p38alpha /PRAK cascade assay format. The kina...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Confluence Life Sciences

US Patent
LigandPNGBDBM175242(US11844801, Compound (M)-I | US9115089, 49)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of MK2 and PRAK by Compound (P)-I and (M)-I, respectively, was investigated to understand selectivity of Compound (P)-I and/or Compound (M...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Confluence Life Sciences

US Patent
LigandPNGBDBM175242(US11844801, Compound (M)-I | US9115089, 49)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of MK2 and PRAK by Compound (P)-I and (M)-I, respectively, was investigated to understand selectivity of Compound (P)-I and/or Compound (M...More data for this Ligand-Target Pair
In DepthDetails US Patent