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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50375145'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50375145
PNG
(CHEMBL271461)
Show SMILES NC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(Nc3ccc(cc3)N3CCNCC3)ncc2c1=O
Show InChI InChI=1S/C27H27N7O2/c28-25(36)23-16-34(21-7-4-17-2-1-3-18(17)14-21)26-22(24(23)35)15-30-27(32-26)31-19-5-8-20(9-6-19)33-12-10-29-11-13-33/h4-9,14-16,29H,1-3,10-13H2,(H2,28,36)(H,30,31,32)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibition of ATP-induced CSF1R autophosphorylation


Bioorg Med Chem Lett 18: 2355-61 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.070
BindingDB Entry DOI: 10.7270/Q26W9BX3
More data for this
Ligand-Target Pair