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Found 9 Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM50021574'
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  4nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human KIT using poly(Glu, Tyr) as substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human recombinant full length c-Kit in presence of ATP by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant human full length KIT using poly (Glu, Tyr) as substrate by alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of KIT (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  53nMAssay Description:Inhibition of c-Kit (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50021574(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of KIT (unknown origin) phosphorylation transfected in human MDA-MB-231 cells incubated for 1 to 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed