Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50190975'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190975((1S)-(2-{4-[(2R)-methyl-3-(4-chlorophenyl)propiony...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190975((1S)-(2-{4-[(2R)-methyl-3-(4-chlorophenyl)propiony...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190975((1S)-(2-{4-[(2R)-methyl-3-(4-chlorophenyl)propiony...)
Affinity DataIC50:  560nMAssay Description:Activity at MC4R assessed as inhibition of alpha MSH-stimulated cAMP production in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190975((1S)-(2-{4-[(2R)-methyl-3-(4-chlorophenyl)propiony...)
Affinity DataIC50:  570nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed