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Found 4 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50190976'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataIC50:  1.70E+3nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataIC50:  1.70E+3nMAssay Description:Activity at MC4R assessed as inhibition of alpha MSH-stimulated cAMP production in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed