Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50503158'
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]JNJ-46281222 from human mGlu2 receptor expressed in CHOK1 cell membranes preincubated for 3 hrs followed by [3H]JNJ-46281222 addi...More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]JNJ-46281222 from human mGlu2 receptor expressed in CHOK1 cell membranes after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in CHOK1 cell membranes assessed as increase in glutamate-induced [35S]GTPgammaS bin...More data for this Ligand-Target Pair