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Found 26 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM50007548'
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataKi:  470nMAssay Description:Binding affinity at Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataKi:  910nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  690nMAssay Description:Agonist activity at mGlu4 receptor expressed in HEK 293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  200nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  500nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  910nMAssay Description:Effect on Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  320nMAssay Description:Stimulation od [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  1.29E+5nMAssay Description:Effective concentration against D309A mutant Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  200nMAssay Description:Effective concentration against Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  510nMAssay Description:Functional activity at rat mGluR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  510nMAssay Description:Agonist activity at rat recombinant mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  96nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells co-transfected with G-protein alpha and EAAC1 assessed as increase in intracellular ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells coexpressing Gq/Gi and EAAC1 assessed as intracellular calcium production measured e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at mGlu4 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at mGlu6 (unknown origin) expressed in HEK293 cells coexpressing chimeric Gq/i protein assessed as [3H]inositol phosphate accumulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat mGluR4 expressed in HEK293 cells assessed as induction of inositol phosphate production by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  320nMAssay Description:Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  310nMAssay Description:Activation of human metabotropic glutamate 4 receptor expressed in golden hamster AV12-664 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  500nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  500nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed