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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM504279'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM504279
PNG
((5S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...)
Show SMILES CN1C(=O)N(C(=O)C[C@]11CCCc2ncccc12)c1c(F)cc(cc1F)C#Cc1ccccc1
Show InChI InChI=1S/C27H21F2N3O2/c1-31-26(34)32(24(33)17-27(31)13-5-10-23-20(27)9-6-14-30-23)25-21(28)15-19(16-22(25)29)12-11-18-7-3-2-4-8-18/h2-4,6-9,14-16H,5,10,13,17H2,1H3/t27-/m0/s1
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US Patent
n/an/an/an/a 76n/an/an/an/a



Hoffmann-La Roche Inc.

US Patent


Assay Description
A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...


US Patent US11034699 (2021)

More data for this
Ligand-Target Pair