Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM504285'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM504285 ((8S)-3′-[2,6-Difluoro-4-(2-phenylethynyl)phe...) Show SMILES CCN1C(=O)N(C(=O)C[C@]11CCCc2ccncc12)c1c(F)cc(cc1F)C#Cc1ccccc1 Show InChI InChI=1S/C28H23F2N3O2/c1-2-32-27(35)33(25(34)17-28(32)13-6-9-21-12-14-31-18-22(21)28)26-23(29)15-20(16-24(26)30)11-10-19-7-4-3-5-8-19/h3-5,7-8,12,14-16,18H,2,6,9,13,17H2,1H3/t28-/m0/s1	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	114	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu4 receptor was generated; for the work with mGlu4 Positive A...				US Patent US11034699 (2021)
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