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Found 2 Enz. Inhib. hit(s) with Target = 'Microtubule-associated protein 2' and Ligand = 'BDBM50167276'
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50167276(CHEMBL3798844)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of recombinant full-length human MetAP2 catalytic domain (110 to 478 residues) expressed in baculovirus using Met-AMC as substrate by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50167276(CHEMBL3798844)
Affinity DataEC50:  1.26E+3nMAssay Description:Inhibition of human MetAP2 in HUVEC cells assessed as accumulation of N-Met 14-3-3gamma after 24 hrs by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed