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Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM418192'
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM418192(2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl]-1-o...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM418192(2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl]-1-o...)
Affinity DataIC50:  1.5nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM418192(2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl]-1-o...)
Affinity DataIC50:  1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM418192(2-{6-[5-chloro-2- (methylamino)pyrimidin-4-yl]-1-o...)
Affinity DataIC50:  1.70nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent