Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM84784'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM84784((6a) BIRB796 | (8a) BIRB796)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM84784((6a) BIRB796 | (8a) BIRB796)
Affinity DataIC50:  25nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM84784((6a) BIRB796 | (8a) BIRB796)
Affinity DataIC50:  393nMpH: 7.5 T: 2°CAssay Description:Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM84784((6a) BIRB796 | (8a) BIRB796)
Affinity DataIC50:  664nMpH: 7.5 T: 2°CAssay Description:Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed