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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM503640'
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM503640(US11034671, Example 28 | US11168095, Example 61)
Affinity DataIC50: <100nMAssay Description:Table 2: Alternatively, the protein kinase activity of the compounds described herein were tested using the ASK1/MAP3K5 assay by Reaction Biology Cor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM503640(US11034671, Example 28 | US11168095, Example 61)
Affinity DataKd:  750nMAssay Description:The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent