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Found 6 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM103776'
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance

US Patent
LigandPNGBDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assay using muscarinic receptors.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance

US Patent
LigandPNGBDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 uL. CHO cell me...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance

US Patent
LigandPNGBDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Affinity DataKi:  0.100nMAssay Description:compounds were performed with [3H]NMS at 1 nM and eleven different test compound concentrations. The test compounds were initially dissolved to a con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance

US Patent
LigandPNGBDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance

US Patent
LigandPNGBDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Affinity DataKi:  0.100nMAssay Description:Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 μL. CHO ce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Theravance

US Patent
LigandPNGBDBM103776(US8551978, I-46 | US8816088, I-46 | US9394275, I-4...)
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
In DepthDetails US Patent