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Found 5 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50403547'
TargetMuscarinic acetylcholine receptor M3(RAT)
Oak Ridge National Laboratory

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.120nMAssay Description:Ability to displace [3H]N-methylscopolamine (NMS) from M3 receptor in rat submaxillary gland homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-4-DAMP from human muscarinic M3 receptor expressed in BHK-21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  2.18nMAssay Description:Displacement of [3H] N-methylscopolamine from human muscarinic M3 receptor expressed in CHOK1 cells after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMuscarinic acetylcholine receptor M3(RAT)
Oak Ridge National Laboratory

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to Muscarinic acetylcholine receptor M3 by measuring its ability to displace [3H]N-methylscopolamine binding in rat submandibulary g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(RAT)
Oak Ridge National Laboratory

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKd:  0.630nMAssay Description:In vitro receptor binding against Muscarinic acetylcholine receptor M3 in rat submandibular gland was determined using [3H]pirenzepineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed