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Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM50263131'
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50263131((+)-7-Methyl-2-exo-[3'-(6-fluoropyridin-2-yl)-5'-p...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50263131((+)-7-Methyl-2-exo-[3'-(6-fluoropyridin-2-yl)-5'-p...)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50263131((+)-7-Methyl-2-exo-[3'-(6-fluoropyridin-2-yl)-5'-p...)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to human alpha4beta2 nAChR expressed in human SHEP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed