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Found 5 Enz. Inhib. hit(s) with Target = 'Neutral amino acid transporter B(0)' and Ligand = 'BDBM50088537'
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088537(CHEMBL6251 | US10189805, Compound 1)
Affinity DataIC50:  9.54E+5nMAssay Description:Inhibition of ASCT2-mediated [3H]glutamine uptake in HEK293 cells after 15 mins by Live-cell glutamine uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088537(CHEMBL6251 | US10189805, Compound 1)
Affinity DataIC50:  9.54E+5nMAssay Description:The glutamine uptake assays in HEK293 cells were carried out in 96 well plates (CulturPlate-96, Perkin Elmer). Cells were plated at a density of 35,0...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088537(CHEMBL6251 | US10189805, Compound 1)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of ASCT2 (unknown origin)-mediated glutamine transportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088537(CHEMBL6251 | US10189805, Compound 1)
Affinity DataIC50:  1.20E+6nMAssay Description:Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral amino acid transporter B(0)(Homo sapiens (Human))
Vanderbilt University Institute Of Imaging Science (Vuiis)

Curated by ChEMBL
LigandPNGBDBM50088537(CHEMBL6251 | US10189805, Compound 1)
Affinity DataIC50:  1.20E+6nMAssay Description:Inhibition of ASCT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed