Found 4 Enz. Inhib. hit(s) with Target = 'Nociceptin receptor' and Ligand = 'BDBM50137562' TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Binding affinity of the compound in CHO cells stably expressing cloned human Opioid receptor like 1 by displacing radioligand [125I]-Tyr14-nociceptinMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Ability to displace [125I]-Tyr14 at nociceptin (NOP) receptorMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonistic activity against nociceptin produced [35S]GTP-gamma-S, binding to Opioid receptor like 1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 6.90E+3nMAssay Description:Agonistic activity of the compound against nociceptin produced GTPgammaS binding to Opioid receptor like 1 expressed in CHO cellsMore data for this Ligand-Target Pair
