Found 4 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM159748'
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Gvk Biosciences
Curated by ChEMBL
Gvk Biosciences
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of N-terminal GST-tagged human TYK2 catalytic domain (871 to 1187 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Gvk Biosciences
Curated by ChEMBL
Gvk Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMpH: 7.4 T: 2°CAssay Description:Test article and assay controls were added to a 384-well plate. Reaction mixtures contained 20 mM HEPES, pH 7.4, 10 mM magnesium chloride, 0.01% bovi...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Gvk Biosciences
Curated by ChEMBL
Gvk Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Test article and assay controls were added to a 384-well plate. Reaction mixtures contained 20 mM HEPES, pH 7.4, 10 mM magnesium chloride, 0.01% bovi...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Gvk Biosciences
Curated by ChEMBL
Gvk Biosciences
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human TYK2 using 5'FAM-KKSRGDYMTMQID as substrate in presence of 1 mM ATP by mobility shift assayMore data for this Ligand-Target Pair