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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM332811'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM332811
PNG
(US10196390, Compound I-83)
Show SMILES Fc1cccc(c1-c1nc2CNC(=O)c2c(Nc2ccc(CC(=O)NC3CCNCC3)cc2)n1)C(F)(F)F
Show InChI InChI=1S/C26H24F4N6O2/c27-18-3-1-2-17(26(28,29)30)21(18)23-35-19-13-32-25(38)22(19)24(36-23)34-15-6-4-14(5-7-15)12-20(37)33-16-8-10-31-11-9-16/h1-7,16,31H,8-13H2,(H,32,38)(H,33,37)(H,34,35,36)
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US Patent
55n/an/an/an/an/an/an/an/a



Nimbus Lakshmi, Inc.

US Patent


Assay Description
The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...


US Patent US10196390 (2019)


BindingDB Entry DOI: 10.7270/Q22809Q4
More data for this
Ligand-Target Pair