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Found 2 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM463609'
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463609(US10781204, Compound I-88 | US11434240, Compound I...)
Affinity DataKi:  0.0500nMAssay Description:Peptide substrate, [KKSRGDYMTMQIG], (20 μM) is prepared in reaction buffer (20 mM Hepes pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/mL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM463609(US10781204, Compound I-88 | US11434240, Compound I...)
Affinity DataKi:  0.0500nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent