Found 3 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2' and Ligand = 'BDBM50261215'
Affinity DataKi: 1.60nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Affinity DataEC50: 224nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-12 induced STAT4 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair