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Found 1 hit Enz. Inhib. hit(s) with Target = 'Norepinephrine Monoamine transporters' and Ligand = 'BDBM50010862'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Norepinephrine Monoamine transporters


(Rattus norvegicus)
BDBM50010862
PNG
(1-[2-Dimethylamino-1-(4-methoxy-phenyl)-ethyl]-cyc...)
Show SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCC1
Show InChI InChI=1S/C16H25NO2/c1-17(2)12-15(16(18)10-4-5-11-16)13-6-8-14(19-3)9-7-13/h6-9,15,18H,4-5,10-12H2,1-3H3
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UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomes


J Med Chem 33: 2899-905 (1990)


Article DOI: 10.1021/jm00172a035
BindingDB Entry DOI: 10.7270/Q20C4WCM
More data for this
Ligand-Target Pair