Found 8 Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 1 group I member 3' and Ligand = 'BDBM50030476'
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 75nMAssay Description:Agonist activity at human CAR expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 510nMAssay Description:Agonist activity at human CAR3 expressed in African green monkey COS-1 cells cotransfected with RXRalpha after 24 hrs by CYP2B6-luciferase reporter g...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at CAR LBD (108 to 348 residues) expressed in human HepG2 cells assessed as receptor binding to PGC1alpha by lanthascreenTR-FRET coa...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Agonist activity at human CARMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 620nMAssay Description:Agonist activity at human CAR transfected in human HepG2 cells cotransfected with CYP2B6 incubated for 23 hrs by luciferase reported gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 49nMAssay Description:Agonist activity at Polyhistidine-tagged human CAR LBD expressed in Escherichia coli by FRET-based assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 49nMAssay Description:Agonist activity at Polyhistidine-tagged human CAR LBD expressed in Escherichia coli by FRET-based assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 3(Homo sapiens (Human))
Phenex Pharmaceuticals
Curated by ChEMBL
Phenex Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 570nMAssay Description:Agonist activity at human constitutive androstane receptor expressed in HepG2 cells co-expressing CYP2B6 incubated for 23 hrs by One-Glo luciferase r...More data for this Ligand-Target Pair