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Found 6 Enz. Inhib. hit(s) with Target = 'Oxytocin receptor' and Ligand = 'BDBM50305506'
TargetOxytocin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305506(5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5...)
Affinity DataKi:  9.5nMAssay Description:Antagonist activity at human cloned oxytocin receptor by cell based beta lactamase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305506(5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]-oxytocin from oxytocin receptor in human uterus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305506(5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]-oxytocin from human oxytocin receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305506(5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human OTR expressed in HEK293 cells assessed as decrease in calcium flux measured after 10 mins in presence of vasopressin by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305506(5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5...)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at human OTR receptor expressed in HEK293FT cells assessed as inhibition of LIT-001-induced response incubated for 30 mins by bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50305506(5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5...)
Affinity DataIC50:  600nMAssay Description:Antagonist activity at human OTR receptor expressed in HEK293FT cells assessed as inhibition of LIT-001-induced calcium release by Aequorin based ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed