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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50336866'
LigandPNGBDBM50336866(3-(2-morpholino-6-(quinolin-3-ylamino)pyrimidin-4-...)
Affinity DataIC50:  61nMAssay Description:Inhibition of PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50336866(3-(2-morpholino-6-(quinolin-3-ylamino)pyrimidin-4-...)
Affinity DataEC50:  370nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser473 in human A2780 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed