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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform' and Ligand = 'BDBM119234'
LigandPNGBDBM119234(US8673906, 2.02 | US9718800, 2.02)
Affinity DataIC50:  7nMT: 2°CAssay Description:Compounds in 100% DMSO were added to assay plates by acoustic dispensing. PI3Kβ was added in a Tris buffer (50 mM Tris pH7.4, 0.05% CHAPS, 2.1 m...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM119234(US8673906, 2.02 | US9718800, 2.02)
Affinity DataIC50:  7nMAssay Description:The inhibition of PI3Kβ, PI3Kα, PI3Kγ and PI3Kδ was evaluated in a Kinase Glo based enzyme activity assay using human recombinant...More data for this Ligand-Target Pair
In DepthDetails US Patent