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Found 2 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform' and Ligand = 'BDBM50449312'
LigandPNGBDBM50449312(CHEMBL3125390)
Affinity DataIC50:  11nMAssay Description:Inhibition of human PI3Kbeta after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50449312(CHEMBL3125390)
Affinity DataIC50:  22nMAssay Description:Inhibition of PI3Kbeta in human PTEN-deficient PC3 cells assessed as Akt phosphorylation at S473More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed