Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50403096'
LigandPNGBDBM50403096(CHEMBL2216895)
Affinity DataKi:  0.200nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403096(CHEMBL2216895)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PI3Kdelta in antiIgM/CD40L-induced human B cells assessed as reduction in cell viability preincubated for 30 mins followed by antiIgM/C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403096(CHEMBL2216895)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as inhibition of antiIgM-induced Akt phosphorylation at ser 473 residue preincubated for 45 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403096(CHEMBL2216895)
Affinity DataIC50:  22nMAssay Description:Inhibition of PI3kdelta in anti-IgD-induced human whole blood cells assessed as reduction in CD69 expression measured after 6 hrs by immunostaining b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403096(CHEMBL2216895)
Affinity DataIC50:  32nMAssay Description:Inhibition of PI3kdelta in anti-IgD-induced human whole blood cells assessed as reduction in Akt phosphorylation at ser 473 residue pretreated with c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed