Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM25084'
LigandPNGBDBM25084(3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]ph...)
Affinity DataIC50:  83nMpH: 7.4 T: 2°CAssay Description:The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25084(3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]ph...)
Affinity DataIC50:  83nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25084(3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]ph...)
Affinity DataIC50:  83nMpH: 7.4 T: 2°CAssay Description:The luminescence-based kinase assay with recombinant phosphatidylinositol 3-kinase (Upstate Cell Signaling Solutions) was used for the determination ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25084(3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]ph...)
Affinity DataKd:  5.30nMAssay Description:Binding constant for PIK3CG kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed