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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet activating factor receptor' and Ligand = 'BDBM50011882'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet activating factor receptor


(Homo sapiens (Human))
BDBM50011882
PNG
(3-[4-(2-Chloro-phenyl)-9-methyl-6H-1-thia-5,7,8,9a...)
Show SMILES Cc1nnc2CN=C(c3cc(sc3-n12)C(CC(=O)N1CCOCC1)N=N)c1ccccc1Cl
Show InChI InChI=1/C22H22ClN7O2S/c1-13-27-28-19-12-25-21(14-4-2-3-5-16(14)23)15-10-18(33-22(15)30(13)19)17(26-24)11-20(31)29-6-8-32-9-7-29/h2-5,10,17,24H,6-9,11-12H2,1H3
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Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Roche Research Center

Curated by ChEMBL


Assay Description
In vitro for platelet activating factor receptor antagonist activity in a binding assay using washed whole dog platelets.


J Med Chem 34: 1440-6 (1991)


Article DOI: 10.1021/jm00108a031
BindingDB Entry DOI: 10.7270/Q2BG2MZ9
More data for this
Ligand-Target Pair