Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50053520'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053520(4-(2-Fluoro-phenyl)-7-[3-(4-hydroxy-tetrahydro-pyr...)
Show SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(c4COC(=O)c4cc3c2)-c2ccccc2F)c1
Show InChI InChI=1S/C30H25FO5/c31-27-7-2-1-6-24(27)28-23-9-8-22(15-20(23)16-25-26(28)18-36-29(25)32)35-17-19-4-3-5-21(14-19)30(33)10-12-34-13-11-30/h1-9,14-16,33H,10-13,17-18H2
Affinity DataIC50: 360nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair