Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50053543'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50053543(7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-...)
Show SMILES COC(=O)c1cc(-c2ccccc2)c2ccc(OCc3cccc(c3)C3(O)CCOCC3)cc2c1
Show InChI InChI=1S/C30H28O5/c1-33-29(31)24-17-23-18-26(10-11-27(23)28(19-24)22-7-3-2-4-8-22)35-20-21-6-5-9-25(16-21)30(32)12-14-34-15-13-30/h2-11,16-19,32H,12-15,20H2,1H3
Affinity DataIC50: 70nMAssay Description:Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenaseMore data for this Ligand-Target Pair