Found 4 Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily T member 1' and Ligand = 'BDBM50557680'
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines
Curated by ChEMBL
Praxis Precision Medicines
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines
Curated by ChEMBL
Praxis Precision Medicines
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of wild-type human Slack expressed in HEK293 cells measured by automated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily T member 1(Rattus norvegicus)
Praxis Precision Medicines
Curated by ChEMBL
Praxis Precision Medicines
Curated by ChEMBL
Affinity DataIC50: 545nMAssay Description:Inhibition of recombinant rat KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines
Curated by ChEMBL
Praxis Precision Medicines
Curated by ChEMBL
Affinity DataIC50: 622nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair