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Found 2 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50054853'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50054853(2-[2-[2-{Acetyl-[(E)-(3-phenyl-acryloyl)]-amino}-3...)
Affinity DataIC50:  7.5nMAssay Description:Antagonistic activity against tritiated agonist (SFFLRR-NH2, at 25 nM) binding to human platelet membranes measured by the GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50054853(2-[2-[2-{Acetyl-[(E)-(3-phenyl-acryloyl)]-amino}-3...)
Affinity DataIC50:  21nMAssay Description:Concentration required to inhibit agonist (SFFLRR-NH2, at 3 uM) induced platelet aggregation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed