Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50054858'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50054858(CHEMBL144504 | Thiophene-2-carboxylic acid [1-[1-[...)
Affinity DataIC50:  25nMAssay Description:Antagonistic activity against tritiated agonist (SFFLRR-NH2, at 25 nM) binding to human platelet membranes measured by the GTPase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50054858(CHEMBL144504 | Thiophene-2-carboxylic acid [1-[1-[...)
Affinity DataEC50:  100nMAssay Description:Concentration of compound required to inhibit agonist (SFFLRR-NH2, at 3 uM) induced platelet aggregation by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed