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Found 13 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50037996'
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity by measuring the inhibition of human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMAssay Description:The compound was evaluated in vitro for the thrombin inhibition.More data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMAssay Description:Inhibitory Activity against bovine thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6nMpH: 7.5Assay Description:Tested for the Inhibition of the catalytic activity of human Thrombin at 25 degree C and pH 7.5.More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6.5nMAssay Description:Inhibitory activity against human thrombin (using Chromozym TH as the substrate)More data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6.5nMAssay Description:Inhibitory effect against bovine thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Bos taurus (Bovine))
Klinikum Der Friedrich-Schiller-Universit£T Jena

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataKi:  6.00E+3nMAssay Description:Binding affinity against bovine ThrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataIC50:  690nMAssay Description:In vitro thrombin inhibitionMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataIC50:  690nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50037996(1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimido...)
Affinity DataEC50:  750nMAssay Description:Effective concentration against thrombin was determinedMore data for this Ligand-Target Pair