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Found 5 Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-2' and Ligand = 'BDBM304239'
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mersana Therapeutics

US Patent
LigandPNGBDBM304239(US10143695, Compound 6A)
Affinity DataIC50:  1.5nMAssay Description:PBD compounds and conjugates thereof were evaluated for their antiproliferation properties in tumor cell lines in vitro using CellTiter-Glo (Promega ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mersana Therapeutics

US Patent
LigandPNGBDBM304239(US10143695, Compound 6A)
Affinity DataIC50:  4.20nMAssay Description:PBD compounds and conjugates thereof were evaluated for their antiproliferation properties in tumor cell lines in vitro using CellTiter-Glo (Promega ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mersana Therapeutics

US Patent
LigandPNGBDBM304239(US10143695, Compound 6A)
Affinity DataIC50:  5.30nMAssay Description:PBD compounds and conjugates thereof were evaluated for their antiproliferation properties in tumor cell lines in vitro using CellTiter-Glo (Promega ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mersana Therapeutics

US Patent
LigandPNGBDBM304239(US10143695, Compound 6A)
Affinity DataIC50:  8.90nMAssay Description:PBD compounds and conjugates thereof were evaluated for their antiproliferation properties in tumor cell lines in vitro using CellTiter-Glo (Promega ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Mersana Therapeutics

US Patent
LigandPNGBDBM304239(US10143695, Compound 6A)
Affinity DataIC50:  17.1nMAssay Description:PBD compounds and conjugates thereof were evaluated for their antiproliferation properties in tumor cell lines in vitro using CellTiter-GloŽ (Promega...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent