Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM420961'
TargetReplicase polyprotein 1ab(BtCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420961(US9975885, Compound 2P | acs.jmedchem.1c00409_ST.4...)
Affinity DataIC50:  3.50E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(BtCoV)
Purdue Research Foundation

US Patent
LigandPNGBDBM420961(US9975885, Compound 2P | acs.jmedchem.1c00409_ST.4...)
Affinity DataIC50:  3.80E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue Research Foundation

US Patent
LigandPNGBDBM420961(US9975885, Compound 2P | acs.jmedchem.1c00409_ST.4...)
Affinity DataIC50:  8.90E+3nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue Research Foundation

US Patent
LigandPNGBDBM420961(US9975885, Compound 2P | acs.jmedchem.1c00409_ST.4...)
Affinity DataIC50:  9.10E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Ligand Info
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)
Purdue Research Foundation

US Patent
LigandPNGBDBM420961(US9975885, Compound 2P | acs.jmedchem.1c00409_ST.4...)
Affinity DataIC50:  2.44E+4nMAssay Description:The inhibitor library was first screened for inhibition of each 3CLpro at a concentration of 100 μM in duplicate assays containing the following...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent