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Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM476339'
TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-OC43)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReplicase polyprotein 1ab(HCoV-229E)
Atea Pharmaceuticals

US Patent
LigandPNGBDBM476339(US10874687, Sofosbuvir)
Affinity DataEC50: >1.00E+5nMAssay Description:Compound activity against coronavirus was based on inhibition of virus induced cytopathogenicity acutely infected with a multiplicity of infection (m...More data for this Ligand-Target Pair
In DepthDetails US Patent