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Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM49122'
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute For Translational Medicine And Pharmacology (Itmp) And Fraunhofer Cluster Of Excellence For Immune Mediated Diseases (Cimd

LigandPNGBDBM49122(2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propi...)
Affinity DataIC50:  140nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute For Translational Medicine And Pharmacology (Itmp) And Fraunhofer Cluster Of Excellence For Immune Mediated Diseases (Cimd

LigandPNGBDBM49122(2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propi...)
Affinity DataIC50:  180nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article