Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM496804'
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Illinois At Chicago

LigandPNGBDBM496804(SARS-CoV-2 PLpro Inhibitor, 34)
Affinity DataIC50:  1.07E+4nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Illinois At Chicago

LigandPNGBDBM496804(SARS-CoV-2 PLpro Inhibitor, 34)
Affinity DataKd:  4.19E+4nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 ug/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed