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Found 3 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM50240436'
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli using DABCYL-KTSAVLQ1SGFRKM-E(EDANS)-NH2 peptide as substrate incubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataIC50:  1.10E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50240436(2-Hydroxy-6-pentadecyl-benzoic acid | 2-hydroxy-6-...)
Affinity DataEC50:  3.98E+3nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed