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Found 2 Enz. Inhib. hit(s) with Target = 'S-adenosylmethionine synthase isoform type-2' and Ligand = 'BDBM507995'
TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Bioscience

US Patent
LigandPNGBDBM507995(7-chloro-1-(imidazol-4-ylmethyl)-4- (methylamino)h...)
Affinity DataIC50: <200nMAssay Description:For the assay, a mixture of 1 mM L-methionine/1 mM ATP (2× final pre-stopped concentration) in assay buffer; MAT2A (2× final pre-stopped concentratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Bioscience

US Patent
LigandPNGBDBM507995(7-chloro-1-(imidazol-4-ylmethyl)-4- (methylamino)h...)
Affinity DataIC50: <200nMAssay Description:MAT2A enzyme is incubated with a test compound in DMSO or DMSO and its substrates (L-methionine and ATP) in a microtiter plate. The enzymatic reactio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent