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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM104183'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM104183
PNG
(US8575145, 60)
Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2cc(F)ccn12
Show InChI InChI=1S/C20H17F2N5O/c21-13-7-9-27-18(10-13)25-26-20(27)15-5-4-12-2-1-3-17(19(12)24-15)28-16-6-8-23-11-14(16)22/h1-5,7,9-10,14,16,23H,6,8,11H2
PDB
MMDB

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Similars

US Patent
n/an/a 26n/an/an/an/a7.422



Array BioPharma Inc

US Patent


Assay Description
The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...


US Patent US8575145 (2013)


BindingDB Entry DOI: 10.7270/Q2M90797
More data for this
Ligand-Target Pair