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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-1' and Ligand = 'BDBM104228'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM104228
PNG
(US8575145, 105)
Show SMILES FCCN1CCC(F)(COc2cccc3ccc(nc23)-c2nnc3ccccn23)CC1
Show InChI InChI=1S/C23H23F2N5O/c24-11-15-29-13-9-23(25,10-14-29)16-31-19-5-3-4-17-7-8-18(26-21(17)19)22-28-27-20-6-1-2-12-30(20)22/h1-8,12H,9-11,13-16H2
PDB
MMDB

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PC cid
PC sid
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Similars

US Patent
n/an/a 8.70n/an/an/an/a7.422



Array BioPharma Inc

US Patent


Assay Description
The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...


US Patent US8575145 (2013)


BindingDB Entry DOI: 10.7270/Q2M90797
More data for this
Ligand-Target Pair