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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase pim-2' and Ligand = 'BDBM104226'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM104226
PNG
(US8575145, 103)
Show SMILES Fc1ccc2nnc(-c3ccc4cccc(OCC5(F)CCNCC5)c4n3)n2c1
Show InChI InChI=1S/C21H19F2N5O/c22-15-5-7-18-26-27-20(28(18)12-15)16-6-4-14-2-1-3-17(19(14)25-16)29-13-21(23)8-10-24-11-9-21/h1-7,12,24H,8-11,13H2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 65.6n/an/an/an/a7.422



Array BioPharma Inc

US Patent


Assay Description
The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...


US Patent US8575145 (2013)


BindingDB Entry DOI: 10.7270/Q2M90797
More data for this
Ligand-Target Pair