BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM497387'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM497387
PNG
(US11007200, Example 3b)
Show SMILES CN[C@]1(CCCC[C@@H]1NCCCc1ccc(F)cc1)c1ccccc1Cl
Show InChI InChI=1S/C22H28ClFN2/c1-25-22(19-8-2-3-9-20(19)23)15-5-4-10-21(22)26-16-6-7-17-11-13-18(24)14-12-17/h2-3,8-9,11-14,21,25-26H,4-7,10,15-16H2,1H3/t21-,22+/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
217n/an/an/an/an/an/an/an/a



MediSynergics, LLC

US Patent


Assay Description
Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...


US Patent US11007200 (2021)

More data for this
Ligand-Target Pair