BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Sigma non-opioid intracellular receptor 1' and Ligand = 'BDBM50068455'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50068455
PNG
(CHEMBL342809 | {4-Oxo-4-[4-(3-phenyl-propyl)-piper...)
Show SMILES CC(C)(C)OC(=O)NCCCC(=O)N1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C22H35N3O3/c1-22(2,3)28-21(27)23-13-7-12-20(26)25-17-15-24(16-18-25)14-8-11-19-9-5-4-6-10-19/h4-6,9-10H,7-8,11-18H2,1-3H3,(H,23,27)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
0.320n/an/an/an/an/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Binding affinity was tested against sigma-1 receptor in guinea brain membranes.


J Med Chem 41: 4950-7 (1999)


Article DOI: 10.1021/jm980143k
BindingDB Entry DOI: 10.7270/Q2NG4PR0
More data for this
Ligand-Target Pair